ITGAL 抗体
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北京 101111
Quick Overview for ITGAL 抗体 (ABIN2567122)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein.
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纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
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亚型
- IgG2a kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-buffered aqueous solution, ph7.2.
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储存条件
- 4 °C
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储存方法
- The product should be stored undiluted at 4°C. Do not freeze.
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- CD11a
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背景
- The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.
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基因ID
- 16408
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UniProt
- P24063
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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