CILP 抗体 (AA 1051-1184) (HRP)
Quick Overview for CILP 抗体 (AA 1051-1184) (HRP) (ABIN2559701)
抗原
See all CILP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1051-1184
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特异性
- The immunogen falls within the Cartilage intermediate layer protein 1 C2 region.
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Cow,Sheep,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CILP
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亚型
- IgG
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anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 603-846) antibody
CILP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 604-864) antibodyCILP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 1051-1184) antibodyCILP 适用: 人, 大鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (Internal Region) antibodyVerified CILP 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP) (AA 129-226) antibodyCILP 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2D10 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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别名
- CILP
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背景
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Synonyms: CILP-1, HsT18872, Cartilage intermediate layer protein 1, Cartilage intermediate-layer protein, CILP, UNQ602/PRO1188
Background: Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.
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基因ID
- 8483
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UniProt
- O75339
抗原
-
