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COMP 抗体 (AA 221-320)

This anti-COMP antibody is a 兔 多克隆 antibody detecting COMP in WB, ELISA, ICC, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN2559644
发货至: 中国

Quick Overview for COMP 抗体 (AA 221-320) (ABIN2559644)

抗原

See all COMP 抗体
COMP (Cartilage Oligomeric Matrix Protein (COMP))

适用

  • 47
  • 32
  • 20
  • 1
  • 1
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  • 1
  • 1

宿主

  • 75
  • 12
  • 1
  • 1

克隆类型

  • 77
  • 12
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This COMP antibody is un-conjugated

应用范围

  • 81
  • 41
  • 27
  • 27
  • 21
  • 12
  • 12
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 9
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-320

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human COMP

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    COMP (Cartilage Oligomeric Matrix Protein (COMP))

    别名

    COMP

    背景

    Synonyms: MED, EDM1, EPD1, PSACH, THBS5, Cartilage oligomeric matrix protein, COMP, Thrombospondin-5, TSP5

    Background: May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7 (By similarity).

    基因ID

    1311

    UniProt

    P49747
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