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TMEM30A 抗体 (AA 251-350) (HRP)

This anti-TMEM30A antibody (ABIN2559507) is a Rabbit Polyclonal antibody detecting TMEM30A in WB, ELISA, IHC (p), IHC (fro). Suitable for Human, Mouse, Rat.
产品编号 ABIN2559507
发货至: 中国

Quick Overview for TMEM30A 抗体 (AA 251-350) (HRP) (ABIN2559507)

抗原

See all TMEM30A 抗体
TMEM30A (Transmembrane Protein 30A (TMEM30A))

适用

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人, 小鼠, 大鼠

宿主

  • 19

克隆类型

  • 19
多克隆

标记

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This TMEM30A antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
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    AA 251-350

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Transmembrane protein 30A

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TMEM30A (Transmembrane Protein 30A (TMEM30A))

    别名

    Transmembrane protein 30A

    背景

    Synonyms: CDC50A, C6orf67, Cell cycle control protein 50A, P4-ATPase flippase complex beta subunit TMEM30A, Transmembrane protein 30A, TMEM30A

    Background: Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes. Involved in uptake of platelet-activating factor (PAF), synthetic drug alkylphospholipid edelfosine, and, probably in association with ATP8B1, of perifosine. Also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.

    基因ID

    55754

    UniProt

    Q9NV96
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