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Aquaporin 4 抗体 (C-Term) (FITC)

This anti-Aquaporin 4 antibody is a 兔 多克隆 antibody detecting Aquaporin 4 in WB, IHC, ICC 和 IF. Suitable for 大鼠.
产品编号 ABIN2486395
发货至: 中国

Quick Overview for Aquaporin 4 抗体 (C-Term) (FITC) (ABIN2486395)

抗原

See all Aquaporin 4 (AQP4) 抗体
Aquaporin 4 (AQP4)

适用

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大鼠

宿主

  • 88
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  • 1
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克隆类型

  • 84
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  • 1
多克隆

标记

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  • 4
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This Aquaporin 4 antibody is conjugated to FITC

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    特异性

    Detects ~35 kDa. May detect larger glycosylated bands ~50 kDa.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Protein A Purified

    免疫原

    Produced against the C-terminal peptide (Sequence N-CTKGSYMEVEDNRSQVETED) of rat aquaporin 4
  • 应用备注

    • WB (1:2000)
    • IHC (1:200)
    • ICC/IF (1:400)
    • optimal dilutions for assays should be determined by the user.

    说明

    0.5 μg/ml of ABIN2486395 was sufficient for detection of aquaporin 4 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Conjugated antibodies should be stored at 4°C
  • 抗原

    Aquaporin 4 (AQP4)

    别名

    Aquaporin 4

    背景

    Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquaporin 4 is constitutively expressed in the basolateral cell membrane of principal collecting duct cells in the kidney and provide a pathway for water to exit these cells (3). It is also expressed in astrocytes and is up regulated by direct insult to the CNS (4). Aquaporin 4 has been proposed as the primary autoimmune target in neuromyelitis optica ( 5, 6).

    基因ID

    25293

    NCBI登录号

    NP_036957

    UniProt

    P47863

    途径

    Sensory Perception of Sound
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