Versican 抗体 (AA 362-585) (Biotin)
Quick Overview for Versican 抗体 (AA 362-585) (Biotin) (ABIN2485745)
抗原
See all Versican (Vcan) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 362-585
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特异性
- Detects >350 kDa.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 362-585 (glycosaminoglycan alpha domain) of mouse Versican core protein
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亚型
- IgG1
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anti-Versican (Vcan) (AA 3301-3396) antibody
Vcan 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Versican (Vcan) (AA 3058-3299) antibodyVcan 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Versican (Vcan) antibodyVcan 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Versican (Vcan) (AA 2958-3209) antibodyVcan 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Versican (Vcan) (AA 362-585) antibodyVcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 unconjugated
anti-Versican (Vcan) (AA 362-585) antibody (HRP)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 HRP
anti-Versican (Vcan) (AA 362-585) antibody (FITC)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 FITC
anti-Versican (Vcan) (AA 362-585) antibody (PE)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 PE
anti-Versican (Vcan) (AA 362-585) antibody (APC)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 APC
anti-Versican (Vcan) (AA 362-585) antibody (PerCP)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 PerCP
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应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2485745 was sufficient for detection of Versican in 20 μg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- Versican (Vcan)
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别名
- Versican
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背景
- Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a Lectinlike sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length anddegree of modification by glycoaminoglycan chains. Accumulation around smooth muscle cells in lesions of athero-sclerosis suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tumor development and may be a reliable marker for clinical diagnosis. The organization of HA- and versican-rich pericellular matrices may faciliatate migration and mitosis by diminishing cell surface adhesivity and affecting cell shape through steric exclusion and the viscous properties of HA proteoglycan gels.
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基因ID
- 13003
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UniProt
- Q62059
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途径
- Glycosaminoglycan Metabolic Process
抗原
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