Erythrocyte Ankyrin 抗体 (AA 1-1881)
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Quick Overview for Erythrocyte Ankyrin 抗体 (AA 1-1881) (ABIN2485521)
抗原
See all Erythrocyte Ankyrin (ANK1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-1881
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特异性
- Detects ~200 kDa. Does not cross-react with Ankyrin-B or Ankyrin-G.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R
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亚型
- IgG2b
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anti-Ankyrin 1, Erythrocytic (ANK1) (C-Term) antibody
ANK1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (HRP)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 HRP
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (FITC)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 FITC
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Biotin)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Biotin
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (PE)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 PE
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (APC)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 APC
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (PerCP)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 PerCP
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 488)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 488
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 594)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 594
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 390)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 390
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应用备注
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
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说明
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A 1:100 dilution of ABIN2485521 was sufficient for detection of Ankyrin R in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C
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- Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
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别名
- Ankyrin R
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背景
- Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane. Ankyrin R, or Ank1, was first discovered in erythrocyres, but has since also been located in the brain and muscles. Mutations are associated with hereditary spehrocytosis and alzheimer's diease (2).
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基因ID
- 286
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NCBI登录号
- NP_000028
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UniProt
- P16157
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途径
- Synaptic Membrane
抗原
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