CLCN3 抗体 (AA 98-115) (PE)
Quick Overview for CLCN3 抗体 (AA 98-115) (PE) (ABIN2485485)
抗原
See all CLCN3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 98-115
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特异性
- Detects ~90 kDa. Does not cross-react with Clcn4 or Clcn5 (based on KO validation results).
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Synthetic peptide amino acids 98-115 (cytoplasmic N-terminus) of rat Clcn3
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亚型
- IgG1
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应用备注
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2485485 was sufficient for detection of Clcn3 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- CLCN3 (Chloride Channel 3 (CLCN3))
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别名
- ClCN3
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背景
- Clcn3 mediates the exchange of chloride ions against protons, and functions as an antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. It may play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could also help neuronal cells to establish short-term memory.
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基因ID
- 84360
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NCBI登录号
- NP_445815
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UniProt
- P51792
抗原
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