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CLCN3 抗体 (AA 98-115) (HRP)

This anti-CLCN3 antibody is a 小鼠 单克隆 antibody detecting CLCN3 in WB, IHC, ICC 和 IF. Suitable for 大鼠.
产品编号 ABIN2485482
发货至: 中国

Quick Overview for CLCN3 抗体 (AA 98-115) (HRP) (ABIN2485482)

抗原

See all CLCN3 抗体
CLCN3 (Chloride Channel 3 (CLCN3))

适用

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大鼠

宿主

  • 33
  • 15
小鼠

克隆类型

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  • 15
单克隆

标记

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This CLCN3 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

S258-5
  • 抗原表位

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    AA 98-115

    特异性

    Detects ~90 kDa. Does not cross-react with Clcn4 or Clcn5 (based on KO validation results).

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Protein G Purified

    免疫原

    Synthetic peptide amino acids 98-115 (cytoplasmic N-terminus) of rat Clcn3

    亚型

    IgG1
  • 应用备注

    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.

    说明

    1 μg/ml of ABIN2485482 was sufficient for detection of Clcn3 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Conjugated antibodies should be stored at 4°C
  • 抗原

    CLCN3 (Chloride Channel 3 (CLCN3))

    别名

    ClCN3

    背景

    Clcn3 mediates the exchange of chloride ions against protons, and functions as an antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. It may play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could also help neuronal cells to establish short-term memory.

    基因ID

    84360

    NCBI登录号

    NP_445815

    UniProt

    P51792
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