ADRA2C 抗体 (AA 442-462) (Atto 488)
Quick Overview for ADRA2C 抗体 (AA 442-462) (Atto 488) (ABIN2485199)
抗原
See all ADRA2C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 442-462
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特异性
- Detects 50 kDa or larger (possibly due to dimerization). Does not cross-react with other adrenergic receptors.
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交叉反应
- 人, 小鼠
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纯化方法
- Protein G Purified
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免疫原
- Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor
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亚型
- IgG1
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应用备注
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2485199 was sufficient for detection of Alpha2C Adrenergic Receptor in 20 μg of COS cells transiently transfected with HA-tagged Alpha- lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
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别名
- Alpha2C Adrenergic
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背景
- The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.
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基因ID
- 152
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NCBI登录号
- NP_000674
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UniProt
- P18825
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途径
- EGFR Signaling Pathway, cAMP Metabolic Process
抗原
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