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Bassoon 抗体 (AA 786-1041) (APC)

This APC-conjugated 兔 多克隆 anti-Bassoon antibody specifically detects Bassoon in IHC 和 WB. The antibody is reactive with 人 samples.
产品编号 ABIN2484541
发货至: 中国
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Quick Overview for Bassoon 抗体 (AA 786-1041) (APC) (ABIN2484541)

抗原

See all Bassoon (BSN) 抗体
Bassoon (BSN)

适用

  • 22
  • 21
  • 14

宿主

  • 23
  • 11

克隆类型

  • 23
  • 11
多克隆

标记

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Bassoon antibody is conjugated to APC

应用范围

  • 26
  • 22
  • 11
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

    • 12
    • 7
    • 2
    • 2
    • 1
    • 1
    AA 786-1041

    特异性

    Detects ~420 kDa. Multiple isoforms can be detected.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Protein A Purified

    免疫原

    NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
  • 应用备注

    • WB (1:1000)
    • IHC (1:400)
    • optimal dilutions for assays should be determined by the user.

    说明

    1 μg/ml of ABIN2484541 was sufficient for detection of Bassoon in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Conjugated antibodies should be stored at 4°C
  • 抗原

    Bassoon (BSN)

    别名

    Bassoon

    背景

    Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors (1).

    基因ID

    8927

    NCBI登录号

    NP_003449

    UniProt

    Q9UPA5
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