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Bassoon 抗体 (AA 786-1041) (Atto 390)

BSN 适用: 人 IHC, WB 宿主: 兔 Polyclonal Atto 390
产品编号 ABIN2484532
发货至: 中国
  • 抗原 See all Bassoon (BSN) 抗体
    Bassoon (BSN)
    抗原表位
    • 13
    • 2
    • 2
    • 1
    • 1
    AA 786-1041
    适用
    • 25
    • 15
    • 14
    • 1
    • 1
    宿主
    • 26
    • 3
    克隆类型
    • 26
    • 3
    多克隆
    标记
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Bassoon antibody is conjugated to Atto 390
    应用范围
    • 20
    • 18
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    特异性
    Detects ~420 kDa. Multiple isoforms can be detected.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein A Purified
    免疫原
    NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
    Top Product
    Discover our top product BSN Primary Antibody
  • 应用备注
    • WB (1:1000)
    • IHC (1:400)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2484532 was sufficient for detection of Bassoon in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    Bassoon (BSN)
    别名
    Bassoon (BSN 产品)
    别名
    Znf231 antibody, ZNF231 antibody, bassoon antibody, bassoon (presynaptic cytomatrix protein) antibody, bassoon presynaptic cytomatrix protein antibody, Bsn antibody, BSN antibody
    背景
    Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors (1).
    基因ID
    8927
    NCBI登录号
    NP_003449
    UniProt
    Q9UPA5
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