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SERPINH1 抗体 (HRP)

This HRP-conjugated 小鼠 单克隆 anti-SERPINH1 antibody (Clone 1C4-1A6) specifically detects SERPINH1 in WB, IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN2484374
发货至: 中国
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Quick Overview for SERPINH1 抗体 (HRP) (ABIN2484374)

抗原

See all SERPINH1 抗体
SERPINH1 (Serpin Family H Member 1 (SERPINH1))

适用

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宿主

  • 59
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小鼠

克隆类型

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单克隆

标记

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This SERPINH1 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

1C4-1A6
  • 特异性

    Detects 47 kDa.

    交叉反应

    纯化方法

    Protein G Purified

    免疫原

    Human HSP47, full length

    亚型

    IgG1 kappa
  • 应用备注

    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.

    说明

    1 μg/ml of ABIN2484374 was sufficient for detection of HSP47 in 20 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Conjugated antibodies should be stored at 4°C
  • 抗原

    SERPINH1 (Serpin Family H Member 1 (SERPINH1))

    别名

    HSP47

    背景

    HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions (1). The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate (2). Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils (3).

    基因ID

    871

    NCBI登录号

    NP_001193943

    UniProt

    P50454
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