SHANK2 抗体 (AA 84-309) (Biotin)
Quick Overview for SHANK2 抗体 (AA 84-309) (Biotin) (ABIN2484049)
抗原
See all SHANK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 84-309
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特异性
- Detects ~160 kDa. Recognizes Shank1, 2 and 3.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 84-309 of rat Shank2
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亚型
- IgG1
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anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody
SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) unconjugated
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (PE)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) PE
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (APC)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) APC
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (PerCP)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) PerCP
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 594)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Atto 594
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 488)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Atto 488
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (Atto 390)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) Atto 390
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (HRP)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) HRP
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 84-309) antibody (FITC)SHANK2 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal N23b-49 (Formerly S23b-49) FITC
anti-SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 728-822) antibodySHANK2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2484049 was sufficient for detection of Shank1-4 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))
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别名
- SHANK
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背景
- Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins (1). Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Studies suggest that Shank2 is expressed in the neurons of the developing retina, and could play a role in the neuronal differentiation of the developing retina (2). Other recent studies suggest that the disruption of glutamate receptors at the Shank postsynaptic platform could contribute to the destruction of the postsynaptic density, which underlies the synaptic dysfunction and loss in Alzheimer's disease (3).
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基因ID
- 171093
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UniProt
- Q9QX74
抗原
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