Metabotropic Glutamate Receptor 5 抗体 (AA 824-1203) (FITC)
Quick Overview for Metabotropic Glutamate Receptor 5 抗体 (AA 824-1203) (FITC) (ABIN2483982)
抗原
See all Metabotropic Glutamate Receptor 5 (GRM5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 824-1203
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特异性
- Detects ~130 kDa (both mGluR1 and mGluR5).
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
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亚型
- IgG1
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应用备注
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2483982 was sufficient for detection of mGluR1/5 glutamate receptor in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
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别名
- mGluR5
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背景
- The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers (1,2).
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基因ID
- 24418
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NCBI登录号
- NP_058708
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UniProt
- P31424
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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