BCAN 抗体 (AA 219-655) (Atto 390)
Quick Overview for BCAN 抗体 (AA 219-655) (Atto 390) (ABIN2483308)
抗原
See all BCAN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 219-655
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特异性
- Detects ~140 kDa (and smaller due to proteolytic cleavage).
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 219-655 of rat Brevican
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亚型
- IgG2b
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anti-Brevican (BCAN) (AA 23-353) antibody
BCAN 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Brevican (BCAN) (AA 219-655) antibody (PerCP)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 PerCP
anti-Brevican (BCAN) (AA 219-655) antibodyBCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 unconjugated
anti-Brevican (BCAN) (AA 219-655) antibody (HRP)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 HRP
anti-Brevican (BCAN) (AA 219-655) antibody (FITC)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 FITC
anti-Brevican (BCAN) (AA 219-655) antibody (Biotin)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 Biotin
anti-Brevican (BCAN) (AA 219-655) antibody (PE)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 PE
anti-Brevican (BCAN) (AA 219-655) antibody (APC)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 APC
anti-Brevican (BCAN) (AA 219-655) antibody (Atto 594)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 Atto 594
anti-Brevican (BCAN) (AA 219-655) antibody (Atto 488)BCAN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S294A-6 Atto 488
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应用备注
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2483308 was sufficient for detection of Brevican in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- BCAN (Brevican (BCAN))
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别名
- Brevican
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背景
- Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.
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基因ID
- 25393
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NCBI登录号
- NP_001028837
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UniProt
- P55068
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途径
- Glycosaminoglycan Metabolic Process
抗原
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