KDELR 抗体 (AA 192-212) (PE)
Quick Overview for KDELR 抗体 (AA 192-212) (PE) (ABIN2481611)
抗原
See all KDELR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 192-212
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特异性
- Detects ~25 kDa.
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交叉反应
- 小鸡, Cow, 犬, Drosophila melanogaster, Hamster, 人, 猴, 小鼠, Pig, 兔, 大鼠, 绵羊, 非洲爪蟾
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纯化方法
- Protein G Purified
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免疫原
- A 21 residue synthetic peptide (amino acids 192-212) based on the bovine KDEL receptor and the peptide coupled to KLH
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亚型
- IgG1
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anti-KDEL Receptor (KDELR) antibody
KDELR 适用: Cow, 人, 小鼠, 小鸡, Drosophila melanogaster, 大鼠, 犬, Hamster, 猴, Pig, 兔, 绵羊, 非洲爪蟾 WB, IHC, ICC, IHC (p), ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-KDEL Receptor (KDELR) (AA 192-212) antibodyKDELR 适用: Cow WB, IP, IHC, ICC, IF 宿主: 小鼠 Monoclonal KR-10 unconjugated
anti-KDEL Receptor (KDELR) (AA 192-212) antibody (HRP)KDELR 适用: Cow WB, IP, IHC, ICC, IF 宿主: 小鼠 Monoclonal KR-10 HRP
anti-KDEL Receptor (KDELR) (AA 192-212) antibody (FITC)KDELR 适用: Cow WB, IP, IHC, ICC, IF 宿主: 小鼠 Monoclonal KR-10 FITC
anti-KDEL Receptor (KDELR) (AA 192-212) antibody (Biotin)KDELR 适用: Cow WB, IP, IHC, ICC, IF 宿主: 小鼠 Monoclonal KR-10 Biotin
anti-KDEL Receptor (KDELR) (AA 192-212) antibody (APC)KDELR 适用: Cow WB, IP, IHC, ICC, IF 宿主: 小鼠 Monoclonal KR-10 APC
anti-KDEL Receptor (KDELR) (AA 192-212) antibody (PerCP)KDELR 适用: Cow WB, IP, IHC, ICC, IF 宿主: 小鼠 Monoclonal KR-10 PerCP
anti-KDEL Receptor (KDELR) (AA 192-212) antibody (Atto 488)KDELR 适用: Cow WB, IP, IHC, ICC, IF 宿主: 小鼠 Monoclonal KR-10 Atto 488
anti-KDEL Receptor (KDELR) (AA 192-212) antibody (Atto 594)KDELR 适用: Cow WB, IP, IHC, ICC, IF 宿主: 小鼠 Monoclonal KR-10 Atto 594
anti-KDEL Receptor (KDELR) (AA 192-212) antibody (Atto 390)KDELR 适用: Cow WB, IP, IHC, ICC, IF 宿主: 小鼠 Monoclonal KR-10 Atto 390
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应用备注
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- WB (1:1000)
- ICC/IF (1:1000)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml was sufficient for detection of KDEL receptor in 20 μg monkey Vero cell lysate by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:AP as the secondary.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.2, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- KDELR (KDEL Receptor (KDELR))
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别名
- KDEL Receptor
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背景
- The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). However, variation on KDEL does occur and other sequences can also give rise to endoplasmic reticulum retention (6). There are three KDEL receptors in mammalian cells, all have a very high degree of sequence identity, and all are located within the cis-Golgi and its intermediate compartments (4). In terms of function, KDEL receptors interact with GAP (GTPase-activating protein) of ARF1, which is involved in COPI dependent vesicle transport, and the KDEL receptor may also be responsible for the recruitment of this ARF1 to membranes which can then aid in the regulation of vesicle budding (3). It is also important to note that the KDEL receptor exhibits extensive sequence identity o yeast protein Erd2p, which is a receptor for the yeast ER retention signal (4, 5).
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基因ID
- 618184
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NCBI登录号
- NP_001069963
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UniProt
- P33946
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途径
- Maintenance of Protein Location
抗原
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