AHSA1 抗体 (PE)
Quick Overview for AHSA1 抗体 (PE) (ABIN2481477)
抗原
See all AHSA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Detects ~38 kDa. Can run up to 45 kDa on SDS Page.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Recombinant Full Length Mouse Aha1 Protein
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亚型
- IgG2a kappa
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应用备注
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- WB (1:1000)
- IHC (1:100)
- ICC/IF (1:1000)
- IP (1:1000)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2481477 was sufficient for detection of Aha1 in 10 μg of rat tissue lysate by colorimetric immunoblot analysis using Goat anti-rat IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.2 mg/mL
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缓冲液
- 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, Storage buffer may change when conjugated
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))
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别名
- AHA1
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背景
- Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).
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基因ID
- 217737
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NCBI登录号
- NP_666148
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UniProt
- Q8BK64
抗原
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