This antibody recognises Human BMP9 (Bone Morphogenic Protein), a member of the TGF-beta superfamily.BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases, resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways. Several antagonist proteins, including, noggin, chordin, gremlin and follistatin, are responsible for modulating the signaling effects of BMPs, through the binding and blocking of receptor ligands, thereby preventing activation.
产品特性
Purified IgG
纯化方法
Purified
免疫原
Synthetic peptide corresponding to the amino acids 87-98 of the native molecule conjugated to keyhole limpet haemocyanin.