Toxin A (AA 2123-2132) 抗体
Cited in 1 publication. This anti-Toxin A antibody is a 兔 多克隆 antibody detecting Toxin A in ELISA. Suitable for Clostridium difficile.
(1 reference)
产品编号 ABIN2476899
发货至:
中国
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Quick Overview for Toxin A (AA 2123-2132) 抗体 (ABIN2476899)
抗原
Toxin A
适用
Clostridium difficile
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA
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抗原表位
- AA 2123-2132
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特异性
- This antibody is specific for Clostridium difficile Toxin A, a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
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产品特性
- Purified IgG
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纯化方法
- Purified
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免疫原
- Synthetic peptide corresponding to the amino acids 2123-2132 of the native molecule conjugated to Keyhole limpet Haemocyanin. Peptide sequence: CTIDGKKYYFN
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亚型
- IgG
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anti-Toxin A antibody
适用: Clostridium difficile ELISA, WB 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 5.0 mg/mL
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: "Clostridium difficile toxins: mechanism of action and role in disease." in: Clinical microbiology reviews, Vol. 18, Issue 2, pp. 247-63, (2005) (PubMed).
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: "Clostridium difficile toxins: mechanism of action and role in disease." in: Clinical microbiology reviews, Vol. 18, Issue 2, pp. 247-63, (2005) (PubMed).
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- Toxin A
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UniProt
- P16154
抗原
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