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IL-17 抗体

This anti-IL-17 antibody is a 大鼠 单克隆 antibody detecting IL-17 in WB, ELISA 和 FACS. Suitable for 小鼠.
产品编号 ABIN2474946
发货至: 中国

Quick Overview for IL-17 抗体 (ABIN2474946)

抗原

See all IL-17 (IL17) 抗体
IL-17 (IL17) (Interleukin 17 (IL17))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL-17 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

TC11-18H10
  • 特异性

    This antibody recognises mouse Interleukin 17, a 32 kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.

    产品特性

    Purified IgG

    纯化方法

    Purified

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL
  • 抗原

    IL-17 (IL17) (Interleukin 17 (IL17))

    别名

    IL-17

    背景

    Synonyms: IL-17A
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