Endothelin 抗体 (C-Term)
Cited in 1 publication.
The 大鼠 单克隆 anti-Endothelin antibody (Clone 3G10) (ABIN2473437) specifically detects Endothelin in IHC (fro) 和 IRMA.
The antibody is reactive with 人 samples.
(1 reference)
产品编号 ABIN2473437
发货至:
中国
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Quick Overview for Endothelin 抗体 (C-Term) (ABIN2473437)
抗原
See all Endothelin 抗体
Endothelin
适用
人
宿主
大鼠
克隆类型
单克隆
标记
This Endothelin antibody is un-conjugated
应用范围
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoradiometric Assay (IRMA)
克隆位点
3G10
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抗原表位
- C-Term
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特异性
- Reacts with the C terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.
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产品特性
- Purified IgG
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纯化方法
- Purified
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免疫原
- Synthetic peptide corresponding to the c-terminal region of human endothelin (C,H,L,D,I,I,W), conjugated to BSA.
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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: "Endothelin is a potent inhibitor of matrix metalloproteinase-2 secretion and activation in rat mesangial cells." in: American journal of physiology. Renal physiology, Vol. 280, Issue 4, pp. F628-35, (2001) (PubMed).
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: "Endothelin is a potent inhibitor of matrix metalloproteinase-2 secretion and activation in rat mesangial cells." in: American journal of physiology. Renal physiology, Vol. 280, Issue 4, pp. F628-35, (2001) (PubMed).
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