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Endothelin 抗体 (C-Term)

This anti-Endothelin antibody is a 大鼠 单克隆 antibody detecting Endothelin in IHC (fro) 和 IRMA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2473437
发货至: 中国

Quick Overview for Endothelin 抗体 (C-Term) (ABIN2473437)

抗原

See all Endothelin 抗体
Endothelin

适用

  • 13
  • 2
  • 1
  • 1
  • 1

宿主

  • 8
  • 5
  • 1
大鼠

克隆类型

  • 8
  • 5
单克隆

标记

  • 10
  • 1
  • 1
  • 1
  • 1
This Endothelin antibody is un-conjugated

应用范围

  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoradiometric Assay (IRMA)

克隆位点

3G10
  • 抗原表位

    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    Reacts with the C terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.

    产品特性

    Purified IgG

    纯化方法

    Purified

    免疫原

    Synthetic peptide corresponding to the c-terminal region of human endothelin (C,H,L,D,I,I,W), conjugated to BSA.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL
  • Yao, Morioka, Li, Oite: "Endothelin is a potent inhibitor of matrix metalloproteinase-2 secretion and activation in rat mesangial cells." in: American journal of physiology. Renal physiology, Vol. 280, Issue 4, pp. F628-35, (2001) (PubMed).

  • 抗原

    Endothelin

    基因ID

    1906, 1907, 1908

    UniProt

    P05305, P14138, P20800
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