Cholera Toxin beta 抗体
Quick Overview for Cholera Toxin beta 抗体 (ABIN2472974)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti cholera toxin beta antibody recognizes the beta subunit of cholera toxin.
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产品特性
- Purified Ig
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纯化方法
- Purified
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免疫原
- Purified choleragenoid
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 4.0 mg/mL
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缓冲液
- Phosphate buffered saline, 0.1% Sodium Azide (NaN3)
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注意事项
- This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended.
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有效期
- 18 months
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: "A hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays." in: Analytical and bioanalytical chemistry, Vol. 398, Issue 5, pp. 1871-81, (2010) (PubMed).
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: "A hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays." in: Analytical and bioanalytical chemistry, Vol. 398, Issue 5, pp. 1871-81, (2010) (PubMed).
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- Cholera Toxin beta
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背景
- The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
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UniProt
- P01556
抗原
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