SLIT1 抗体 (AA 155-173)
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Quick Overview for SLIT1 抗体 (AA 155-173) (ABIN2470344)
抗原
See all SLIT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 155-173
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Slit Homolog 1 antibody was raised against amino acids 155 - 173 of Slit Homolog 1 (Mouse).
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应用备注
- Slit Homolog 1 antibody can be used in Western Blot, and immunohistochemistry starting at 20 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store Slit Homolog 1 antibody at 4 °C or -20 °C.
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- SLIT1 (Slit Homolog 1 (SLIT1))
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别名
- Slit Homolog 1
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背景
- SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein. This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Alternative splicing isoforms have been identified for Slit1 protein.
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基因ID
- 6585
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UniProt
- O75093
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途径
- Regulation of Cell Size
抗原
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