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Cullin 3 抗体 (N-Term)

This anti-Cullin 3 antibody is a 兔 多克隆 antibody detecting Cullin 3 in WB, IHC, ELISA 和 IP. Suitable for 人.
产品编号 ABIN2470220
发货至: 中国

Quick Overview for Cullin 3 抗体 (N-Term) (ABIN2470220)

抗原

See all Cullin 3 (CUL3) 抗体
Cullin 3 (CUL3)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cullin 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 抗原表位

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    N-Term

    纯化方法

    Delipidation and Defibrination

    免疫原

    Cullin 3 antibody was raised against amino acids 1-12 from the N-Terminus of Cullin 3 (Human).
  • 应用备注

    Cullin 3 antibody can be used in ELISA starting at 1:1000, and immunohistochemistry starting at 10 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.01 % Sodium azide

    注意事项

    As with all antibodies avoid freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store Cullin 3 antibody at 4 °C or -20 °C.
  • 抗原

    Cullin 3 (CUL3)

    别名

    Cullin 3

    背景

    Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 3 is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cul3 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul3 may also contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Unlike Cul1 and Cul2, Cul3 seems not to be a part of the SCF complex consisting of CUL1, RBX1, SKP1 and SKP2. Cul3 also interacts with RNF7 and is part of a complex with TIP120A/CAND1, Cyclin E and RBX1.

    基因ID

    8452

    UniProt

    Q13618

    途径

    M Phase
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