电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CBLC 抗体 (AA 444 - 458)

This anti-CBLC antibody is a 兔 多克隆 antibody detecting CBLC in WB, ELISA, IHC, IF 和 IP. Suitable for 人.
产品编号 ABIN2470158
发货至: 中国

Quick Overview for CBLC 抗体 (AA 444 - 458) (ABIN2470158)

抗原

See all CBLC 抗体
CBLC (Cbl proto-oncogene C (CBLC))

适用

  • 35
  • 2
  • 1

宿主

  • 30
  • 5

克隆类型

  • 30
  • 5
多克隆

标记

  • 25
  • 2
  • 2
  • 2
  • 2
  • 2
This CBLC antibody is un-conjugated

应用范围

  • 34
  • 22
  • 17
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    AA 444 - 458

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    CBLC antibody was raised against amino acids 444 - 458 of CBLC (Human).
  • 应用备注

    CBLC antibody can be used in Western Blot, and immunohistochemistry starting at 10 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies avoid freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store CBLC antibody at 4 °C or -20 °C.
  • 抗原

    CBLC (Cbl proto-oncogene C (CBLC))

    别名

    CBLC

    背景

    Cbl-c is also known as signal transduction protein CBL-C, SH3-binding protein CBL-C, CBL-3, and RING finger protein 57. Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl-c (a.k.a. Cbl-3) is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Cbl-c knock out mice show no obvious phenotype. Thus, the physiological role of Cbl-c is not known.

    基因ID

    23624

    UniProt

    Q9ULV8

    途径

    EGFR Signaling Pathway
You are here:
Chat with us!