TMEM123
适用: 人, 小鼠, 大鼠
WB, FACS, IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy5
应用备注
TMEM123 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.
限制
仅限研究用
状态
Liquid
缓冲液
PBS, 0.05 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
As with all antibodies avoid freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
TMEM123 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
抗原
TMEM123
(Transmembrane Protein 123 (TMEM123))
别名
TMEM123
背景
Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110- kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.