TLX1 抗体 (AA 300-330)
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北京 101111
Quick Overview for TLX1 抗体 (AA 300-330) (ABIN2470149)
抗原
See all TLX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-330
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纯化方法
- Protein G Column
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免疫原
- TLX1 antibody was raised against amino acids 300 - 330 of TLX1 (Human).
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亚型
- IgG
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anti-T-Cell Leukemia Homeobox 1 (TLX1) (AA 300-330), (AA 306-318) antibody
TLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, Bat, 猴, 小鸡, 马, Hamster WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (AA 163-191) antibodyTLX1 适用: 小鼠, 人 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (AA 1-190) antibodyTLX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (AA 144-193) antibodyTLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, 豚鼠, Bat, 猴, 小鸡, 马, 斑马鱼, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (C-Term) antibodyTLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, 豚鼠, Bat, 猴, 小鸡, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (N-Term) antibodyTLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, 豚鼠, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (N-Term) antibodyTLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- TLX1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 0.2 % gelatin, 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- TLX1 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
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- TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))
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别名
- TLX1
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背景
- HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region. It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus. HOX11 is required for maintenance of the developing spleen and cell survival. The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus. It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator. The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35,q24) or t(10:14)(q24,qll) translocation. The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates a specific subset of tumor-associated target genes. HOX 11 gene translocation has been attributed to T-cell leukemia and lymphoid neoplasias.
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基因ID
- 3195
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UniProt
- P31314
抗原
-
