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HAVCR1 抗体 (AA 200-300)

This anti-HAVCR1 antibody (ABIN2470107) is a Rabbit Polyclonal antibody detecting HAVCR1 in WB, IHC. Suitable for Human, Mouse.
产品编号 ABIN2470107
发货至: 中国

Quick Overview for HAVCR1 抗体 (AA 200-300) (ABIN2470107)

抗原

See all HAVCR1 抗体
HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This HAVCR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 200-300

    纯化方法

    Protein G Column

    免疫原

    HAVCR1 antibody was raised against amino acids 200 - 300 of HAVCR1 (Human).

    亚型

    IgG
  • 应用备注

    HAVCR1 antibody can be used in immunohistochemistry starting at 5 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, 0.05 % BSA, 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store HAVCR1 antibody at 4 °C for short term applications. For long term storage, aliquot and -20 °C.
  • 抗原

    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

    别名

    HAVCR1

    物质类

    Virus

    背景

    HAVCR1, a 359 A.A Class 1 integral membrane glycoprotein, is used by Hepatitis A virus to infect humans. It consists of a conserved N-terminal Cys-rich region, IgV (Immunoglobulin Variable region like) domain and a TSP-rich mucin domain in the extracellular region followed by a highly conserved tyrosine kinase phosphorylation motif in the cytoplasmic region. HAVCR1 is expressed on terminally differentiated CD4+ Th2 cells and regulates cytokine production. It plays an important role in the regulation of immune responses in the development of asthma and allergic responses. Its expression is critically upregulated in dedifferentiated kidney cells, thus indicating a possible role in regeneration of proximal tubule epithelium in Kidneys. HAVCR1 has shown to be upregulated in renal carcinomas, suggesting its role in tumor progression and metastasis.

    基因ID

    26762

    UniProt

    Q96D42
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