CXCR4 抗体
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北京 101111
Quick Overview for CXCR4 抗体 (ABIN2470068)
抗原
See all CXCR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity Chromatography
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亚型
- IgG2a
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应用备注
- CXCR4 antibody can be used in immunohistochemistry starting at 10 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.2, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze thaw cycles
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储存条件
- 4 °C
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储存方法
- Store CXCR4 antibody at 4 °C, Avoid Freezing
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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别名
- CXCR4
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背景
- CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.
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基因ID
- 7852
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UniProt
- P61073
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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