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PDE9A 抗体 (Internal Region)

This anti-PDE9A antibody is a 兔 多克隆 antibody detecting PDE9A in IHC. Suitable for 人, 犬, 猴 和 Gibbon.
产品编号 ABIN2469457
发货至: 中国

Quick Overview for PDE9A 抗体 (Internal Region) (ABIN2469457)

抗原

See all PDE9A 抗体
PDE9A (phosphodiesterase 9A (PDE9A))

适用

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人, 犬, 猴, Gibbon

宿主

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克隆类型

  • 22
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多克隆

标记

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This PDE9A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    Internal Region

    特异性

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    PDE9A antibody was raised against a peptide located near the internal domain of PDE9A (Human).
  • 应用备注

    PDE9A antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, 0.1 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies avoid freeze/thaw cycles.

    储存条件

    4 °C/-80 °C

    储存方法

    PDE9A antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
  • 抗原

    PDE9A (phosphodiesterase 9A (PDE9A))

    别名

    PDE9A

    背景

    Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.

    基因ID

    5152

    UniProt

    O76083
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