PDE8B 抗体 (Internal Region)
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Quick Overview for PDE8B 抗体 (Internal Region) (ABIN2469456)
抗原
See all PDE8B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- PDE8B antibody was raised against a peptide located near the internal domain of PDE8B (Human).
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应用备注
- PDE8B antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 0.1 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-80 °C
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储存方法
- PDE8B antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
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- PDE8B (phosphodiesterase 8B (PDE8B))
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别名
- PDE8B
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背景
- Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.
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基因ID
- 8622
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UniProt
- O95263
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
抗原
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