SPHK1 抗体 (N-Term)
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Quick Overview for SPHK1 抗体 (N-Term) (ABIN2469349)
抗原
See all SPHK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- SPHK1 antibody was raised against a peptide located in the N-Terminal domain of SPHK1 (Human).
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应用备注
- SPHK1 antibody can be used in immunohistochemistry starting at 40 μg/mL, and flow cytometry.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 0.1 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies avoid freeze/thaw cycles.
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储存条件
- 4 °C/-80 °C
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储存方法
- SPHK1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
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- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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别名
- SPHK1
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背景
- Sphingosine kinase (SPHK) phosphorylates sphingosine to form a bioactive lipid mediate, sphingosine 1-phosphate (S1P or SPP). S1P is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival while extracellularly it is a ligand for EDG 1. Expression of SPHK1 and subsequent production of S1P promotes the G1-S transition, protects cells from apoptosis, stimulates migration and angiogenesis, and induces tumor formation in mice.
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基因ID
- 8877
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UniProt
- Q9NYA1
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途径
- VEGF Signaling
抗原
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