DUSP6 抗体 (AA 135-280)
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Quick Overview for DUSP6 抗体 (AA 135-280) (ABIN2468007)
抗原
See all DUSP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 135-280
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纯化方法
- Immunoaffinity Purified
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应用备注
- Dual specificity phosphatase 6 antibody can be used for the detection of Dual specificity phosphatase 6 by Western Blot.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline. No preservatives added.
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储存液
- Without preservative
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- 4 °C/-20 °C
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储存方法
- DUSP6 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
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别名
- DUSP6
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背景
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This protein product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm.
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分子量
- 15.1 kDa (calculated)
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基因ID
- 1848
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NCBI登录号
- NP_001937
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UniProt
- Q16828
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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