Dual specificity phosphatase 6 antibody can be used for the detection of Dual specificity phosphatase 6 by Western Blot.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
Phosphate-Buffered Saline. No preservatives added.
储存液
Without preservative
注意事项
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
储存条件
4 °C/-20 °C
储存方法
DUSP6 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
抗原
DUSP6
(Dual Specificity Phosphatase 6 (DUSP6))
别名
DUSP6
背景
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This protein product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm.