Adam23 抗体 (AA 72-144)
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Quick Overview for Adam23 抗体 (AA 72-144) (ABIN2467991)
抗原
See all Adam23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 72-144
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纯化方法
- Immunoaffinity Purified
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应用备注
- ADAM 23 antibody can be used for the detection of ADAM 23 by Western Blot.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline. No preservatives added.
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储存液
- Without preservative
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- 4 °C/-20 °C
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储存方法
- ADAM23 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- Adam23 (ADAM Metallopeptidase Domain 23 (Adam23))
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别名
- ADAM23
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背景
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FUNCTION: May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.
SUBUNIT: Ligand for integrin alpha-V/γ,-3.
SIMILARITY: Contains 1 peptidase M12B domain.
SUBCELLULAR LOCATION: Membrane, single-pass type I membrane protein (Potential). Secreted protein. Isoform Gamma.
TISSUE SPECIFICITY: Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.
DEVELOPMENTAL STAGE: Highly expressed in the fetal brain.
DOMAIN:A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.
SUMMARY: This protein is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is highly expressed in the brain and may function as an integrin ligand in the brain. -
分子量
- 91.9 kDa (calculated)
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基因ID
- 8745
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NCBI登录号
- NP_003803
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UniProt
- O75077
抗原
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