CXCR4 抗体 (AA 6-41)
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Quick Overview for CXCR4 抗体 (AA 6-41) (ABIN2467958)
抗原
See all CXCR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-41
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纯化方法
- Immunoaffinity Purified
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应用备注
- C-X-C chemokine receptor type 4 antibody can be used for the detection of C-X-C chemokine receptor type 4 by Western Blot.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline. No preservatives added.
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储存液
- Without preservative
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- 4 °C/-20 °C
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储存方法
- CXCR4 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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别名
- CXCR4
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背景
- FUNCTION: Receptor for the C-X-C chemokine SDF-1. Transduces a signal by increasing the intracellular calcium ions level. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodelling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a primary receptor for some HIV-2 isolates and as a coreceptor with CD4 for HIV-1 X4 viruses (lymphocyte-tropic HIV-1 viruses, also called syncytium-inducing (SI) strains). Promotes Env-mediated fusion of the virus.
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分子量
- 39.7 kDa (calculated)
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基因ID
- 7852
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NCBI登录号
- NP_003458
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UniProt
- P61073
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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