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ZAP70 抗体 (truncated)

This anti-ZAP70 antibody is a 小鼠 单克隆 antibody detecting ZAP70 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN2464121
发货至: 中国

Quick Overview for ZAP70 抗体 (truncated) (ABIN2464121)

抗原

See all ZAP70 抗体
ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ZAP70 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

3D2A4
  • 抗原表位

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    truncated

    免疫原

    Ni-NTA purified truncated recombinant ZAP70 expressed in E. Coli strain BL21 (DE3).

    亚型

    IgG1
  • 应用备注

    Western Blot:1:500 - 1:2,000
    IHC(P):1:500 - 1:2,000
    IHC(F):1:500 - 1:2,000
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    -20 °C

    储存方法

    ZAP70 monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原

    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

    别名

    ZAP70

    背景

    ZAP70(zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Zap70 controls TCR(T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the zap-70 gene. ZAP-70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.

    基因ID

    7535

    UniProt

    P43403

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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