ZAP70 抗体 (truncated)
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北京 101111
Quick Overview for ZAP70 抗体 (truncated) (ABIN2464121)
抗原
See all ZAP70 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- truncated
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免疫原
- Ni-NTA purified truncated recombinant ZAP70 expressed in E. Coli strain BL21 (DE3).
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亚型
- IgG1
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应用备注
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Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- -20 °C
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储存方法
- ZAP70 monoclonal antibody can be stored at -20 °C, stable for one year.
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- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
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别名
- ZAP70
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背景
- ZAP70(zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Zap70 controls TCR(T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the zap-70 gene. ZAP-70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.
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基因ID
- 7535
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UniProt
- P43403
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途径
- TCR Signaling, Ubiquitin Proteasome Pathway
抗原
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