Lipase A 抗体 (truncated)
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Quick Overview for Lipase A 抗体 (truncated) (ABIN2464075)
抗原
See all Lipase A (LIPA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- truncated
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纯化方法
- Antibody is purified by protein A affinity chromatography.
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免疫原
- Ni-NTA purified truncated recombinant LAL expressed in E. Coli strain BL21 (DE3).
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亚型
- IgG2a
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应用备注
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Western Blot:Dilution 1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS containing 0.03 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- -20 °C
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储存方法
- LAL monoclonal antibody can be stored at -20 °C, stable for one year.
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- Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
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别名
- LAL
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背景
- Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.
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基因ID
- 3988
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UniProt
- P38571
抗原
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