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FER 抗体 (truncated)

This anti-FER antibody is a 小鼠 单克隆 antibody detecting FER in WB 和 ELISA. Suitable for 人.
产品编号 ABIN2464050
发货至: 中国

Quick Overview for FER 抗体 (truncated) (ABIN2464050)

抗原

See all FER 抗体
FER (FER Tyrosine Kinase (FER))

适用

  • 70
  • 61
  • 17
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1

宿主

  • 84
  • 9
小鼠

克隆类型

  • 84
  • 9
单克隆

标记

  • 45
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This FER antibody is un-conjugated

应用范围

  • 78
  • 32
  • 26
  • 26
  • 15
  • 13
  • 12
  • 6
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA

克隆位点

5D2C4-8D8C12
  • 抗原表位

    • 26
    • 15
    • 10
    • 8
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    truncated

    免疫原

    Ni-NTA purified truncated recombinant FER-His expressed in E. Coli strain BL21 (DE3).

    亚型

    IgG1
  • 应用备注

    Western Blot:1:500 - 1:2,000
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    -20 °C

    储存方法

    FER monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原

    FER (FER Tyrosine Kinase (FER))

    别名

    FER

    背景

    FER (fer tyrosine kinase) is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases, which shares a functional domain and is involved in signaling pathways through receptor tyrosine kinases (RTK) and cytokine receptors. The Fes /Fps family is distinct from c-Src, c-Abl and related nRTKs and was originally distinguished as a homolog to retroviral oncoproteins. In vivo, Fer kinase assembles into homotrimers via conserved coiled-coil domains. The N-terminal coiled-coil domains of Fer can autophosphorylate in trans, thereby regulating their cellular function through differential phosphorylation states. Growth factor exposure can induce tyrosine phosphorylation of Fer and recruitment of Fer to RTK complexes containing p85. It is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, and has been shown to be expressed in vascular endothelial cells. Fer is implicated in insulin signaling, cell-cell signaling, human prostatic proliferative diseases, and is involved in the regulation of G1 progression.

    基因ID

    2241

    UniProt

    P16591
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