FER 抗体 (truncated)
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北京 101111
Quick Overview for FER 抗体 (truncated) (ABIN2464050)
抗原
See all FER 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- truncated
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免疫原
- Ni-NTA purified truncated recombinant FER-His expressed in E. Coli strain BL21 (DE3).
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亚型
- IgG1
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anti-FER Tyrosine Kinase (FER) antibody
FER 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 5D2C4 unconjugated
anti-FER Tyrosine Kinase (FER) (AA 1-300) antibodyFER 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 1457CT181-12-17 unconjugated
anti-FER Tyrosine Kinase (FER) antibodyFER 适用: 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal 1487CT794-8-50 unconjugated
anti-FER Tyrosine Kinase (FER) (AA 782-811), (C-Term) antibodyFER 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB03222 unconjugated
anti-FER Tyrosine Kinase (FER) antibodyFER 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (Ser376) antibodyFER 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (AA 521-536), (Middle Region) antibodyFER 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人, 犬, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- -20 °C
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储存方法
- FER monoclonal antibody can be stored at -20 °C, stable for one year.
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- FER (FER Tyrosine Kinase (FER))
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别名
- FER
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背景
- FER (fer tyrosine kinase) is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases, which shares a functional domain and is involved in signaling pathways through receptor tyrosine kinases (RTK) and cytokine receptors. The Fes /Fps family is distinct from c-Src, c-Abl and related nRTKs and was originally distinguished as a homolog to retroviral oncoproteins. In vivo, Fer kinase assembles into homotrimers via conserved coiled-coil domains. The N-terminal coiled-coil domains of Fer can autophosphorylate in trans, thereby regulating their cellular function through differential phosphorylation states. Growth factor exposure can induce tyrosine phosphorylation of Fer and recruitment of Fer to RTK complexes containing p85. It is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, and has been shown to be expressed in vascular endothelial cells. Fer is implicated in insulin signaling, cell-cell signaling, human prostatic proliferative diseases, and is involved in the regulation of G1 progression.
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基因ID
- 2241
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UniProt
- P16591
抗原
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