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Arrestin 3 抗体

ARRB2 适用: 人, 犬 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2463123
发货至: 中国
  • 抗原 See all Arrestin 3 (ARRB2) 抗体
    Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
    适用
    • 47
    • 27
    • 26
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 犬
    宿主
    • 39
    • 5
    • 3
    克隆类型
    • 42
    • 5
    多克隆
    标记
    • 28
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Arrestin 3 antibody is un-conjugated
    应用范围
    • 39
    • 17
    • 15
    • 13
    • 13
    • 12
    • 12
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ARRB2.
    Top Product
    Discover our top product ARRB2 Primary Antibody
  • 应用备注
    ARRB2 antibody can be used for detection of ARRB2 by ELISA at 1:312500. ARRB2 antibody can be used for detection of ARRB2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store ARRB2 antibody at -20 °C.
  • 抗原
    Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
    别名
    ARRB2 (ARRB2 产品)
    别名
    ARRB2 antibody, arb2 antibody, arr2 antibody, arrestin antibody, barr2 antibody, betaarr2 antibody, ARB2 antibody, ARR2 antibody, BARR2 antibody, BARRES antibody, AI326910 antibody, AW122872 antibody, arrb2 antibody, zgc:64007 antibody, arrestin beta 2 antibody, arrestin, beta 2 antibody, arrestin beta 2 L homeolog antibody, arrestin, beta 2b antibody, ARRB2 antibody, arrb2 antibody, Arrb2 antibody, arrb2.L antibody, arrb2b antibody
    背景
    Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
    分子量
    44 kDa, 46 kDa
    基因ID
    409
    NCBI登录号
    NP_945355
    UniProt
    A8K4I6
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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