MAFK 抗体
Quick Overview for MAFK 抗体 (ABIN2463076)
抗原
See all MAFK 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAFK.
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anti-Transcription Factor MafK (MAFK) antibody
MAFK 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 8C5 unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 豚鼠, Hamster, 猴, 小鸡, 非洲爪蟾, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafK (MAFK) (N-Term) antibodyMAFK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- MAFK antibody can be used for detection of MAFK by ELISA at 1:312500. MAFK antibody can be used for detection of MAFK by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAFK antibody at -20 °C.
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- MAFK (Transcription Factor MafK (MAFK))
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别名
- MAFK
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背景
- The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites.The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD, MIM 176000) and ferrochelatase (FECH, MIM 177000). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM].
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分子量
- 17 kDa
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基因ID
- 7975
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NCBI登录号
- NP_002351
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UniProt
- O60675
抗原
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