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SEC63 抗体

This anti-SEC63 antibody is a 兔 多克隆 antibody detecting SEC63 in WB 和 ELISA. Suitable for 人, 小鼠 和 犬.
产品编号 ABIN2463021
发货至: 中国

Quick Overview for SEC63 抗体 (ABIN2463021)

抗原

See all SEC63 抗体
SEC63 (SEC63 Homolog (SEC63))

适用

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人, 小鼠, 犬

宿主

  • 18
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克隆类型

  • 20
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多克隆

标记

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This SEC63 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SEC63.
  • 应用备注

    SEC63 antibody can be used for detection of SEC63 by ELISA at 1:62500. SEC63 antibody can be used for detection of SEC63 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SEC63 antibody at -20 °C.
  • 抗原

    SEC63 (SEC63 Homolog (SEC63))

    别名

    SEC63

    背景

    The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

    分子量

    88 kDa

    基因ID

    11231

    NCBI登录号

    NP_009145

    UniProt

    Q9UGP8

    途径

    ER-Nucleus Signaling
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