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UBE2D1 抗体

This anti-UBE2D1 antibody is a 兔 多克隆 antibody detecting UBE2D1 in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN2462648
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for UBE2D1 抗体 (ABIN2462648)

抗原

See all UBE2D1 抗体
UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

适用

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人, 小鼠, 大鼠, 犬

宿主

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克隆类型

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多克隆

标记

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This UBE2D1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2D1.
  • 应用备注

    UBE2D1 antibody can be used for detection of UBE2D1 by ELISA at 1:62500. UBE2D1 antibody can be used for detection of UBE2D1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store UBE2D1 antibody at -20 °C.
  • 抗原

    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

    别名

    UBE2D1

    背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

    分子量

    16 kDa, 42 kDa

    基因ID

    7321

    NCBI登录号

    NP_003329

    UniProt

    P51668

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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