RGS18 抗体
Quick Overview for RGS18 抗体 (ABIN2462635)
抗原
See all RGS18 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS18.
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anti-Regulator of G-Protein Signalling 18 (RGS18) (C-Term) antibody
Verified RGS18 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 28-84) antibodyRGS18 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 1-235) antibodyRGS18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (N-Term) antibodyRGS18 适用: 人, 大鼠, 犬, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 41-90) antibodyRGS18 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signalling 18 (RGS18) (AA 120-169) antibodyRGS18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- RGS18 antibody can be used for detection of RGS18 by ELISA at 1:62500. RGS18 antibody can be used for detection of RGS18 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RGS18 antibody at -20 °C.
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- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
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别名
- RGS18
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背景
- RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
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分子量
- 26 kDa
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基因ID
- 64407
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NCBI登录号
- NP_570138
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UniProt
- Q9NS28
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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