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S1PR5 抗体

This anti-S1PR5 antibody is a 兔 多克隆 antibody detecting S1PR5 in WB, ELISA 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬 和 Drosophila melanogaster.
产品编号 ABIN2462615
发货至: 中国

Quick Overview for S1PR5 抗体 (ABIN2462615)

抗原

See all S1PR5 抗体
S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

适用

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人, 小鼠, 大鼠, 犬, Drosophila melanogaster

宿主

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克隆类型

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多克隆

标记

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This S1PR5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EDG8.
  • 应用备注

    EDG8 antibody can be used for detection of EDG8 by ELISA at 1:312500. EDG8 antibody can be used for detection of EDG8 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store EDG8 antibody at -20 °C.
  • 抗原

    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

    别名

    EDG8

    背景

    EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G (i/0)alpha and G (12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

    分子量

    16 kDa, 17 kDa, 14 kDa

    基因ID

    53637

    UniProt

    Q9H228
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