EXOSC6 抗体
Quick Overview for EXOSC6 抗体 (ABIN2462323)
抗原
See all EXOSC6 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by peptide affinity chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EXOSC6.
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anti-Exosome Component 6 (EXOSC6) (N-Term) antibody
EXOSC6 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 小鼠, 大鼠, Cow, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- EXOSC6 antibody can be used for detection of EXOSC6 by ELISA at 1:62500. EXOSC6 antibody can be used for detection of EXOSC6 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store EXOSC6 antibody at -20 °C.
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- EXOSC6 (Exosome Component 6 (EXOSC6))
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别名
- EXOSC6
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背景
- EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly (A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly (A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
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分子量
- 30 kDa
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基因ID
- 118460
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NCBI登录号
- NP_478126
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UniProt
- Q5RKV6
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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