PCBP1 抗体
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北京 101111
Quick Overview for PCBP1 抗体 (ABIN2462201)
抗原
See all PCBP1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCBP1.
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anti-Poly(rC) Binding Protein 1 (PCBP1) (Middle Region) antibody
PCBP1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 100-200) antibodyPCBP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 181-280) antibodyPCBP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 181-280) antibodyPCBP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 208-257) antibodyPCBP1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) antibodyPCBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) antibodyPCBP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 223-234) antibodyVerified PCBP1 适用: 人, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 234-247) antibodyVerified PCBP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 1 (PCBP1) (AA 201-250) antibodyPCBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- PCBP1 antibody can be used for detection of PCBP1 by ELISA at 1:62500. PCBP1 antibody can be used for detection of PCBP1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCBP1 antibody at -20 °C.
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- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
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别名
- PCBP1
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背景
- PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This intronless gene is thought to be generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
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分子量
- 39 kDa
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基因ID
- 5093
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NCBI登录号
- NP_006187
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UniProt
- Q15365
抗原
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