PCBP2 抗体
Quick Overview for PCBP2 抗体 (ABIN2462179)
抗原
See all PCBP2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCBP2.
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anti-Poly(rC) Binding Protein 2 (PCBP2) antibody
PCBP2 适用: 人 WB, IF, ICC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-362) antibodyPCBP2 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-130) antibodyPCBP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-362) antibodyPCBP2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6B6 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-362) antibodyPCBP2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (Middle Region) antibodyPCBP2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 171-293) antibodyPCBP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (AA 1-363) antibodyPCBP2 适用: 人 WB, ELISA, IHC, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) antibodyPCBP2 适用: 人, 小鼠, 斑马鱼 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly(rC) Binding Protein 2 (PCBP2) (Internal Region) antibodyPCBP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- PCBP2 antibody can be used for detection of PCBP2 by ELISA at 1:312500. PCBP2 antibody can be used for detection of PCBP2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCBP2 antibody at -20 °C.
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- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
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别名
- PCBP2
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背景
- PCBP2 appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. This protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This gene and PCBP-1 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes.The protein encoded by this gene appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly (rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1 intronless gene which has similar functions. This gene and PCBP-1 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. It also has two processed pseudogenes PCBP2P1 and PCBP2P2. There are presently two alternatively spliced transcript variants described for this gene.
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分子量
- 40 kDa, 38 kDa
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基因ID
- 5094
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NCBI登录号
- NP_005007
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UniProt
- Q6IPF4
抗原
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