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TSG101 抗体

TSG101 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2461785
发货至: 中国
  • 抗原 See all TSG101 抗体
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    适用
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    人, 小鼠, 大鼠, 犬, 斑马鱼
    宿主
    • 61
    • 11
    克隆类型
    • 52
    • 20
    多克隆
    标记
    • 47
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    This TSG101 antibody is un-conjugated
    应用范围
    • 57
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by protein A chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TSG101.
    Top Product
    Discover our top product TSG101 Primary Antibody
  • 应用备注
    TSG101 antibody can be used for detection of TSG101 by ELISA at 1:312500. TSG101 antibody can be used for detection of TSG101 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TSG101 antibody at -20 °C.
  • 抗原
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    别名
    TSG101 (TSG101 产品)
    别名
    CG9712 antibody, DmTSG101 antibody, Dmel\\CG9712 antibody, ESCRT-I antibody, Tsg101 antibody, burs antibody, dTSg101 antibody, dTsg101 antibody, dVps23 antibody, ept antibody, tsg101 antibody, vps23 antibody, TSG101 antibody, MGC76193 antibody, TSG10 antibody, VPS23 antibody, AI255943 antibody, CC2 antibody, Rw antibody, zgc:86926 antibody, tumor susceptibility 101 antibody, Tumor susceptibility gene 101 antibody, Tumor Susceptibility Gene homolog antibody, tumor susceptibility gene 101 antibody, tumor susceptibility 101a antibody, tumor susceptibility 101 L homeolog antibody, TSG101 antibody, tsg-101 antibody, tsg101 antibody, Tsg101 antibody, tsg101a antibody, tsg101.L antibody
    背景
    TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. TSG101 contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. TSG101 may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of TSG101 appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in TSG101 gene occur in high frequency in breast cancer. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
    分子量
    44 kDa
    基因ID
    7251
    NCBI登录号
    NP_006283
    UniProt
    Q99816
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