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TSG101 抗体

This anti-TSG101 antibody is a 兔 多克隆 antibody detecting TSG101 in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠, 犬 和 斑马鱼.
产品编号 ABIN2461785
发货至: 中国

Quick Overview for TSG101 抗体 (ABIN2461785)

抗原

See all TSG101 抗体
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

适用

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人, 小鼠, 大鼠, 犬, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This TSG101 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TSG101.
  • 应用备注

    TSG101 antibody can be used for detection of TSG101 by ELISA at 1:312500. TSG101 antibody can be used for detection of TSG101 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TSG101 antibody at -20 °C.
  • 抗原

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    别名

    TSG101

    背景

    TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. TSG101 contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. TSG101 may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of TSG101 appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in TSG101 gene occur in high frequency in breast cancer. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

    分子量

    44 kDa

    基因ID

    7251

    NCBI登录号

    NP_006283

    UniProt

    Q99816
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